Separation of Deformable Hydrogel Microparticles in Deterministic Lateral Displacement Devices

To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deformability and their overall behavior in the device. Future work will expand the approach to a range of particle shapes and to particles with varied hydrogel composition to independently control the mechanical properties of the material.